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NAT10 Recombinant Rabbit mAb (S-2547-125) Other Proteins although not required

SKU: 2748386825

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Description

although not required

Differentially expressed in ovarian carcinoma 2 (DOC-2)

and its ectodomain is proteolytically cleaved by ADAM10 and ADAM17 to release a soluble fragment (sTREM2) that is elevated in cerebrospinal fluid in early AD and can itself act as an immunomodulatory ligand amplifying microglial responses to pathology

and mature B cells

It is also up regulated on immunosuppressive tumor-associated macrophages as well as on macrophages and monocytes at chronic inflammatory sites including rheumatoid arthritis synovium and glioblastoma

NAT10 Recombinant Rabbit mAb (S-2547-125) Other Proteins although not requiredProduct Specification Host Rabbit Antigen NAT10 Synonyms RNA cytidine acetyltransferase; 18S rRNA cytosine acetyltransferase; N acetyltransferase 10; N acetyltransferase like protein (hALP); ALP s; KIAA1709 Immunogen Synthetic Peptide Location Nucleus Accession Q9H0A0 Clone Number S 2547 125 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu, Ms, Rt Positive Sample 293T, HeLa, A549, NIH 3T3, mouse brain, mouse heart, C6, rat

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