ActRIIA Enzyme Activity Inhibitor Screening Kit Size:1000T Species Human Accession P04049-1 Amino

Species Human Accession P04049-1 Amino Acid Sequence S306-F648(end)，N-terminal GST tag

While the enzyme can catalyze thioether bond formation between some electrophilic chemicals and GSH

and its dysregulation is associated with diseases such as mitochondrial complex I deficiency and aging

The approximately 100-aa-long propeptide domain actually contains not only the cleavage moiety but also the mature peptide

which has a wide range of biological activities on T cells and natural killer cells

ActRIIA Enzyme Activity Inhibitor Screening Kit Size:1000T Species Human Accession P04049-1 AminoProduct Specification Species Human Background STX 001, the leading program of Supercede, is a novel oral small molecule Activin Receptor Type II (ACTRII) kinase inhibitor currently in preclinical development for the treatment of obesity. In Phase II clinical studies, inhibition of the ACTRII signaling pathway has been shown to significantly reduce fat while stimulating an increase in lean body mass (muscle). For patients with obesity, achieving