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Synthesis of Bispecific Antibodies using Genetically Encoded Unnatural Amino Acids
Backbone Modification
Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic
Antigen Delivery Controlled by an On-Demand Photorelease Angew
1) Patterson
PODS-GAA-pSar12-Dab(N3)-OH RDC-8171 Synthesis of Bispecific Antibodies usingReferences: Toda, N.; et al. Rapid, Stable, Chemoselective Labeling of Thiols with JuliaKocienski like Reagents: A Serum Stable Alternative to Maleimide Based Protein Conjugation. Angew. Chem., Int. Ed. (2013), 52, 12592 12596. DOI: 10. 1002 anie. 201306241 Keywords: PODS; Azido; Click Chemistry; Protein Conjugation Patterson, J. T.; et al. Improving the Serum Stability of Site Specific Antibody Conjugates with Sulfone Linkers. Bioconjugate Chem.
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